Tag "publications"

Scientists from HSE MIEM have developed a new approach to modelling electrothermal processes in high-power electronic circuits on printed circuit boards (PCB). The method allows engineers to quickly and accurately predict how electronic components heat up during operation, helping prevent overheating and potential failures. The results have been published in Russian Microelectronics.

An international team of researchers, including physicists from HSE MIEM, has demonstrated that nonmagnetic impurities can help more accurately reveal Majorana zero modes—quantum states considered promising building blocks for quantum computing. The researchers found that these impurities shift the energy levels that typically obscure the Majorana signal, while leaving the mode itself largely unaffected, thereby making its spectral peak more distinct. The study has been published in Research.

Researchers at the HSE Faculty of Computer Science benchmarked more than 200,000 model configurations for predicting financial asset prices and realised volatility, showing that performance can be improved by filtering out noise at specific frequencies in advance. This technique increased accuracy in 65% of cases. The authors also developed their own algorithm, which achieves accuracy comparable to that of the best models while requiring less computational power. The study has been published in Applied Soft Computing.

Experts from the HSE Institute for Statistical Studies and Economics of Knowledge have examined industrial PhD programmes across 19 countries worldwide. The analysis shows that the key components of an effective model include co-funding by universities, industry, and government; dual academic supervision; and flexible intellectual property arrangements. The findings have been published in Foresight and STI Governance.

Scientists at HSE University have identified a molecular mechanism underlying aggressive breast cancer. They found that the signals supporting tumour growth originate not from the tumour itself but from its microenvironment. The researchers also demonstrated that reduced levels of the IGFBP6 protein in the tumour microenvironment lead to the accumulation of macrophages—immune cells associated with a higher risk of cancer recurrence. These findings already make it possible to assess patient risk more accurately and may, in the future, enable the development of drugs that target cells of the tumour microenvironment. The study has been published in Current Drug Therapy.

Scientists at HSE University have discovered that in preeclampsia—one of the most severe complications of pregnancy—the placenta remodels its lipid metabolism, reducing its own cholesterol synthesis while increasing cholesterol transfer to the foetus. This compensatory mechanism helps sustain foetal nutrition but accelerates placental deterioration and may lead to preterm birth. The study findings have been published in Frontiers in Molecular Biosciences.

HSE researchers evaluated the accuracy of technology forecasts in the transportation sector over the past 50 years and found that the average accuracy rate does not exceed 25%, with the lowest accuracy observed in aviation and rail transport. According to the scientists, this is due to limitations of the forecasting method and the inherent complexities of the sector. The study findings have been published in Technological Forecasting and Social Change.

A team of scientists, including researchers from HSE University, has proposed a method for assessing stress resilience using physiological markers derived from wearable devices and saliva samples. The participants who adapted better to stress showed higher heart rate variability, higher zinc concentrations in saliva, and lower potassium levels.  The findings were published in the Journal of Molecular Neuroscience.

Researchers from the HSE Center for Language and Brain and the Mental Health Research Centre have proposed a new method of linguistic analysis that enables the distinction between normal and pathological ageing. Using this approach, they showed that patterns in patients’ word choices during verbal fluency tests allow clinicians to more accurately differentiate clinically significant impairments from subjective memory complaints. Incorporating this type of analysis into clinical practice could improve the accuracy of early dementia diagnosis. The results have been published in Applied Neuropsychology: Adult.

Researchers from the HSE Center for Language and Brain used magnetoencephalography to study how the brains of adults and children respond to words during reading. They showed that in children the brain takes longer to process words that are frequently used in everyday speech, while rare words and pseudowords are processed in the same way—slowly and in parts. With age, the system is reorganised: high-frequency words shift to a fast route, whereas new letter combinations are still analysed slowly. The study was published in the journal Psychophysiology.