HSE Development Programme until 2030

Researchers from the HSE Center for Language and Brain used magnetoencephalography to study how the brains of adults and children respond to words during reading. They showed that in children the brain takes longer to process words that are frequently used in everyday speech, while rare words and pseudowords are processed in the same way—slowly and in parts. With age, the system is reorganised: high-frequency words shift to a fast route, whereas new letter combinations are still analysed slowly. The study was published in the journal Psychophysiology.

An international team including researchers from the HSE Faculty of Computer Science has presented KoWit-24, an annotated dataset of 2,700 Russian-language Kommersant news headlines containing wordplay. The dataset enables an assessment of how artificial intelligence detects and interprets wordplay. Experiments with five large language models show that even advanced systems still make mistakes, and that interpreting wordplay is more challenging for them than detecting it. The results were presented at the RANLP conference; the paper is available on Arxiv.org, and the dataset and the code for reproducing the experiments are available on GitHub.

Scientists at HSE University have investigated the effect of parks on the cognitive and emotional resources of city dwellers. The researchers compared brain electrical activity in 30 participants while they watched videos of walks through parks and along busy highways. The results showed that green urban environments with trees produce a consistent effect across individuals, helping the brain calm down and relax. By contrast, walks along busy streets were found to be distracting. The findings have been published in Scientific Reports.

Scientists at HSE MIEM, in collaboration with colleagues from China, have developed a method to improve the durability of perovskite solar cells by addressing iodine loss from the material. The researchers introduced quaternary ammonium molecules into the perovskite structure; these molecules form strong electrostatic pairs with iodine ions, effectively anchoring them within the crystal lattice. As a result, the solar cells retain more than 92% of their power after a thousand hours of operation at 85°C. The study has been published in Advanced Energy Materials.

An international team, including researchers from HSE University, has created the first comprehensive map of quadruplexes—unstable DNA structures involved in gene regulation. For the first time, scientists have shown that these structures function in pairs: one is located in a DNA region that initiates gene transcription, while the other lies in a nearby region that enhances this process. In healthy tissues, quadruplexes regulate tissue-specific genes, whereas in cancerous tissues they influence genes responsible for cell growth and division. These findings may contribute to the development of new anticancer drugs that target quadruplexes. The study has been published in Nucleic Acids Research.

The HSE Graduate School of Business and the Tsinghua University School of Economics and Management (Tsinghua SEM) have signed a cooperation and exchange agreement aimed at developing joint education and research programs and strengthening academic dialogue between Russia and China.

Scientists at the HSE AI Research Centre have developed a novel approach to determining robustness in deep learning models. Their method works eight times faster than an exhaustive model search and significantly reduces the need for manual verification. It can be applied to particle physics problems using neural networks of various architectures. The study has been published in IEEE Access.

Eating habits can be shaped not only by the authority of medical experts but also through ordinary conversations among friends. Researchers at HSE University have shown that advice from peers to reduce sugar consumption is just as effective as advice from experts. The study's findings have been published in Frontiers in Nutrition.

Researchers from the HSE Center for Language and Brain took part in brain surgery on a patient who had been seriously wounded in the SMO. A shell fragment approximately five centimetres long entered through the eye socket, penetrated the cranial cavity, and became lodged in the brain, piercing the temporal lobe responsible for language. Surgeons at the Burdenko Main Military Clinical Hospital removed the foreign object while the patient remained conscious. During the operation, neurolinguists conducted language tests to ensure that language function was preserved.

An international team, including researchers from HSE University, examined an unusual SARS-CoV-2 sample obtained from an HIV-positive patient. Genetic analysis revealed multiple mutations and showed that the virus had been evolving inside the patient’s body for two years. This finding supports the theory that the virus can persist in individuals for years, gradually accumulate mutations, and eventually spill back into the population. The study's findings have been published in Frontiers in Cellular and Infection Microbiology.