Tag "frontiers of science"

A team of scientists, including researchers from HSE University, has proposed a method for assessing stress resilience using physiological markers derived from wearable devices and saliva samples. The participants who adapted better to stress showed higher heart rate variability, higher zinc concentrations in saliva, and lower potassium levels.  The findings were published in the Journal of Molecular Neuroscience.

Researchers from the HSE Center for Language and Brain and the Mental Health Research Centre have proposed a new method of linguistic analysis that enables the distinction between normal and pathological ageing. Using this approach, they showed that patterns in patients’ word choices during verbal fluency tests allow clinicians to more accurately differentiate clinically significant impairments from subjective memory complaints. Incorporating this type of analysis into clinical practice could improve the accuracy of early dementia diagnosis. The results have been published in Applied Neuropsychology: Adult.

Researchers from the HSE Center for Language and Brain used magnetoencephalography to study how the brains of adults and children respond to words during reading. They showed that in children the brain takes longer to process words that are frequently used in everyday speech, while rare words and pseudowords are processed in the same way—slowly and in parts. With age, the system is reorganised: high-frequency words shift to a fast route, whereas new letter combinations are still analysed slowly. The study was published in the journal Psychophysiology.

An international team including researchers from the HSE Faculty of Computer Science has presented KoWit-24, an annotated dataset of 2,700 Russian-language Kommersant news headlines containing wordplay. The dataset enables an assessment of how artificial intelligence detects and interprets wordplay. Experiments with five large language models show that even advanced systems still make mistakes, and that interpreting wordplay is more challenging for them than detecting it. The results were presented at the RANLP conference; the paper is available on Arxiv.org, and the dataset and the code for reproducing the experiments are available on GitHub.

Scientists at HSE University have investigated the effect of parks on the cognitive and emotional resources of city dwellers. The researchers compared brain electrical activity in 30 participants while they watched videos of walks through parks and along busy highways. The results showed that green urban environments with trees produce a consistent effect across individuals, helping the brain calm down and relax. By contrast, walks along busy streets were found to be distracting. The findings have been published in Scientific Reports.

HSE University experts have analysed students’ digital footprints and shown for the first time that final grades depend on one’s personal approach to an online course. Balanced students have proven to be more successful than those who follow a more traditional and practical approach. The findings from this study will help create a more adaptive and personalised educational system. This research has been published in the journal The Internet and Higher Education.

Scientists at HSE MIEM, in collaboration with colleagues from China, have developed a method to improve the durability of perovskite solar cells by addressing iodine loss from the material. The researchers introduced quaternary ammonium molecules into the perovskite structure; these molecules form strong electrostatic pairs with iodine ions, effectively anchoring them within the crystal lattice. As a result, the solar cells retain more than 92% of their power after a thousand hours of operation at 85°C. The study has been published in Advanced Energy Materials.

An international team, including researchers from HSE University, has created the first comprehensive map of quadruplexes—unstable DNA structures involved in gene regulation. For the first time, scientists have shown that these structures function in pairs: one is located in a DNA region that initiates gene transcription, while the other lies in a nearby region that enhances this process. In healthy tissues, quadruplexes regulate tissue-specific genes, whereas in cancerous tissues they influence genes responsible for cell growth and division. These findings may contribute to the development of new anticancer drugs that target quadruplexes. The study has been published in Nucleic Acids Research.

Mathematician Ivan Remizov from HSE University–Nizhny Novgorod and the Institute for Information Transmission Problems of the Russian Academy of Sciences has made a conceptual breakthrough in the theory of differential equations. He has derived a universal formula for solving problems that had been considered unsolvable in quadratures for more than 190 years. This result fundamentally reshapes one of the oldest areas of mathematics and has potential to have important implications for fundamental physics and economics. The paper has been published in Vladikavkaz Mathematical Journal.

Valeria Vinogradova, a researcher at HSE University, together with British colleagues, studied how language proficiency affects cognitive processing in deaf adults. The study showed that higher language proficiency—regardless of whether the language is signed or spoken—is associated with higher activity and stronger functional connectivity within the brain network responsible for cognitive task performance. The findings have been published in Cerebral Cortex.